エストロゲン依存性症状
エストロゲン依存性症状(Estrogen-dependent condition, disease, disorder, or syndrome)は、体内のエストロゲン活性の存在に一部または全部が依存している、あるいは過敏な医学的状態を指す[要出典]。
エストロゲン依存性症状には、乳房痛[1][2]、乳腺線維症[3]、乳腺房増殖(英語版)、巨大乳房[4][5]、女性化乳房[6]、乳癌[7]、女児の思春期早発症[8]、肝斑[9]、月経痛[10][11]、子宮内膜症[12]、子宮内膜増殖症[13]、腺筋症(英語版)[13]、子宮筋腫[14]、子宮体癌[14]、卵巣癌[15]、男性の肝硬変やクラインフェルター症候群[16]などでの高エストロゲン症などが知られている。
このような症状は、タモキシフェンやクロミフェンなどの選択的エストロゲン受容体モジュレーター(SERM)、フルベストラントなどのエストロゲン受容体阻害薬、アナストロゾールやエキセメスタンなどのアロマターゼ阻害薬[7]、リュープロレリン、セトロレリクスなどのゴナドトロピン放出ホルモン(GnRH)アナログ、ダナゾール、ゲストリノン、酢酸メゲストロール、酢酸メドロキシプロゲステロンなどの抗ゴナドトロピン薬等の抗エストロゲン作用を有する薬剤で治療する事が出来る[17][18]。
関連項目
- エストロゲン不応症候群(英語版)
- アンドロゲン依存性症状
出典
- ^ CURRENT OBSTETRICS and GYNECOLOGY by MUKHERJEE. Jaypee Brothers Publishers. (2007). pp. 347–. ISBN 978-81-8061-996-0. https://books.google.com/books?id=hvm5IDZ15TEC&pg=PA347
- ^ Leonard J. Deftos (1 January 1998). Clinical Essentials of Calcium and Skeletal Disorders. Professional Communications. pp. 226–. ISBN 978-1-884735-39-4. https://books.google.com/books?id=dOAH6tBMXmAC&pg=PA226
- ^ Linda Laucella (1 September 2002). The Hormone Decision. Contemporary Books. ISBN 978-0-07-141615-3. https://archive.org/details/hormonedecision700lauc
- ^ Maria Siemionow; Marita Eisenmann-Klein (13 January 2010). Plastic and Reconstructive Surgery. Springer Science & Business Media. pp. 423–. ISBN 978-1-84882-513-0. https://books.google.com/books?id=9WFZ1pE0AFMC&pg=PA423
- ^ Merril D. Smith (8 September 2014). Cultural Encyclopedia of the Breast. Rowman & Littlefield Publishers. pp. 73–. ISBN 978-0-7591-2332-8. https://books.google.com/books?id=qrCCBAAAQBAJ&pg=PA73
- ^ Vasan; R.S. (1 January 1998). Textbook of Medicine. Orient Blackswan. pp. 1113–. ISBN 978-81-250-1266-5. https://books.google.com/books?id=qLZHaBf9l7YC&pg=PA1113
- ^ a b Edward J. Parish; W. David Nes (14 January 1997). Biochemistry and Function of Sterols. CRC Press. pp. 26–27. ISBN 978-0-8493-7674-0. https://books.google.com/books?id=yyQ0yPi9SHUC&pg=PA26
- ^ Michael Crocetti; Michael A. Barone; Frank A. Oski (2004). Oski's Essential Pediatrics. Lippincott Williams & Wilkins. pp. 564–. ISBN 978-0-7817-3770-8. https://books.google.com/books?id=I3Kh1cNJxyUC&pg=PA564
- ^ W. Steven Pray (2006). Nonprescription Product Therapeutics. Lippincott Williams & Wilkins. pp. 639–. ISBN 978-0-7817-3498-1. https://books.google.com/books?id=XU1sMK1djVAC&pg=PA639
- ^ Sharon L. Lewis; Shannon Ruff Dirksen; Margaret M. Heitkemper; Linda Bucher (2 December 2013). Medical-Surgical Nursing: Assessment and Management of Clinical Problems, Single Volume. Elsevier Health Sciences. pp. 1281–. ISBN 978-0-323-08678-3. https://books.google.com/books?id=owEyAgAAQBAJ&pg=PA1281
- ^ Guy I. Benrubi (28 March 2012). Handbook of Obstetric and Gynecologic Emergencies. Lippincott Williams & Wilkins. pp. 287–. ISBN 978-1-4511-4797-1. https://books.google.com/books?id=NIWe9at-nDUC&pg=PA287
- ^ Togas Tulandi; David Redwine (9 December 2003). Endometriosis: Advances and Controversies. CRC Press. pp. 125–. ISBN 978-0-8247-5864-6. https://books.google.com/books?id=Q9ldvHVtWCUC&pg=PA125
- ^ a b Reed Dunnick; Carl M. Sandler; Jeffrey H. Newhouse (15 October 2012). Textbook of Uroradiology. Lippincott Williams & Wilkins. pp. 377–378. ISBN 978-1-4511-0916-0. https://books.google.com/books?id=FicoXBfd0oIC&pg=PA377
- ^ a b Edward J. Parish; W. David Nes (14 January 1997). Biochemistry and Function of Sterols. CRC Press. pp. 26–27. ISBN 978-0-8493-7674-0. https://books.google.com/books?id=yyQ0yPi9SHUC&pg=PA26
- ^ Aurel Lupulescu (24 October 1990). Hormones and Vitamins in Cancer Treatment. CRC Press. pp. 33–. ISBN 978-0-8493-5973-6. https://books.google.com/books?id=VddUa-2cp-YC&pg=PA33
- ^ Eugene A. DeFelice (1 May 2002). Breast Cancer: Web Resource Guide for Consumers, Healthcare Providers, Patients, and Physicians. iUniverse. pp. 65–. ISBN 978-0-595-22651-1. https://books.google.com/books?id=KZeYfP2m8nwC&pg=PA65
- ^ Bruce A. Chabner; Dan L. Longo (8 November 2010). Cancer Chemotherapy and Biotherapy: Principles and Practice. Lippincott Williams & Wilkins. pp. 651–673. ISBN 978-1-60547-431-1. https://books.google.com/books?id=WL4arNFsQa8C&pg=PA667
- ^ Debmalya Barh (13 October 2014). Omics Approaches in Breast Cancer: Towards Next-Generation Diagnosis, Prognosis and Therapy. Springer. pp. 488–. ISBN 978-81-322-0843-3. https://books.google.com/books?id=94nLBAAAQBAJ&pg=PA488
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